A study found that the STAMINA lifestyle program, which includes supervised exercise and dietary advice, reduced quality of life deterioration in men receiving androgen deprivation therapy.

Key facts
- •The STAMINA program reduced the deterioration in quality of life by up to one-third for men on androgen deprivation therapy.
- •The study was a five-year project funded by the National Institute for Health Research in the United Kingdom.
- •Participants in the STAMINA group received a combination of aerobic and resistance exercise, dietary advice, and behavioral support.
- •Nuffield Health intends to expand the program to cover breast and bowel cancer by 2030.
- •The American Cancer Society estimates over 330,000 new prostate cancer cases in the U.S. in 2026.
Researchers in the United Kingdom found that a structured lifestyle regimen known as STAMINA can improve quality of life and reduce fatigue in men undergoing androgen deprivation therapy (ADT) for prostate cancer. The study, published in The Lancet Oncology, monitored 700 participants across 15 National Health Service facilities. Results indicated that the program, which combines supervised exercise, dietary guidance, and behavioral support, helped mitigate negative side effects associated with common cancer treatments.
By the numbers
Study Methodology and Findings
The research involved 700 men with a median age of 71, who were randomly assigned to either the STAMINA program or a standard supplementary treatment group between January 2022 and January 2023. Over a 12-month period, more than 80% of participants in the STAMINA group attended their scheduled sessions. Those in the program reported less fatigue and better cancer-specific quality of life compared to those receiving standard care.
Future Implementation and Expert Perspective
Following the study's results, Nuffield Health has launched a new cancer activity program to make a version of STAMINA available to patients. The organization plans to expand this initiative to include breast and bowel cancer patients across 50,000 medical facilities by 2030. While experts note the program's benefits for quality of life, they clarify that the study did not assess whether these lifestyle interventions translate into longer survival rates.
Timeline
- January 2022Participants began being randomly assigned to study groups.
- September 4Study findings were published in The Lancet Oncology.
- June 2024Follow-up examinations for the study concluded.
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This article was independently rewritten by ManyPress editorial AI from reporting originally published by Healthline.


